Isn't It Time to Retire the Oral Glucose Tolerance Test for Diabetes Screening and Diagnosis?

Isn't it time to retire the oral glucose tolerance test for diabetes screening and diagnosis?

Longer time to peak glucose during the oral glucose tolerance test increases cardiovascular risk score and diabetes prevalence

INTRODUCTION The pattern of glucose levels during an oral glucose tolerance test (OGTT) may be useful for predicting diabetes or cardiovascular disease (CVD). Our aim was to determine whether the time to peak glucose during the OGTT is associated with CVD risk scores and diabetes. METHODS Individuals with impaired fasting glucose (IFG) were enrolled in this observational study. Participants w...

Hemoglobin A1c for the diagnosis of diabetes: To replace or to guide oral glucose tolerance tests?

UNLABELLED Aims/Introduction:  To evaluate if hemoglobin A1c (A1C) can replace the use of the oral glucose tolerance test (OGTT) to diagnose diabetes in Chinese patients. MATERIALS AND METHODS   Subjects without pre-existing diabetes were included in this community-based study. Each participant received a 75-g OGTT and A1C tests. RESULTS   A total of 1362 subjects, 512 men and 850 women, ag...

Hemoglobin A1c Versus Oral Glucose Tolerance Test in Postpartum Diabetes Screening

OBJECTIVE To determine the usefulness of measuring hemoglobin A(1c) (A1C), alone or combined with the fasting glucose test, compared with the oral glucose tolerance test (OGTT) for the reassessment of the carbohydrate metabolism status in postpartum women with a history of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS We evaluated the status of carbohydrate metabolism by pe...

Pathogenetic Mechanisms and Cardiovascular Risk Differences between HbA1c and oral glucose tolerance test for the diagnosis of glucose tolerance

RESEARCHDESIGNANDMETHODSdA total of 844 subjects (44%men; age 49.56 11 years; BMI 296 5 kg/m) participated in this study. Parameters ofb-cell functionwere derived from deconvolution of the plasma C-peptide concentration after a 75-g OGTT and insulin sensitivity assessed by homeostasis model assessment of insulin resistance (IR). Cardiovascular risk profile was based on determination of plasma l...